Liquid Chromatography Lab
In Chemir’s Liquid Chromatography (LC) laboratory, our scientists identify and quantify non-volatile materials. A variety of specialized instrumentation and detection methods are available to customize an analysis for your specific needs.
High Performance Liquid Chromatograpy (HPLC) is routinely performed using an ultraviolet (UV) detector. Materials that do not have strong UV absorption may be detected by coupling the flow to an Evaporative Light Scattering Detector (ELSD). The mobile phase is nebulized and evaporates; the remaining solute particles are detected by scattering light. If extreme sensitivity is required, limits of detection in the parts-per-billion (ppb) may be obtained in this lab by derivatization of the molecule of interest and detection with a fluorescence detector. The Mass Spectrometry (MS) detector is used to identify analytes by mass. The ion trap MS can be used to further fragment the parent ions into daughter ions to definitively elucidate structures of unknown analytes or verify the presence of specific molecules.
Gel Permeation Chromatography (GPC) is used to measure the molecular weight distribution and polydispersity of polymers. Our elevated temperature capabilities allow for the solubilization and analysis of difficult matrices.
Ion Chromatography (IC) separates, identifies, and quantifies anions and cations in a sample matrix. The identification of salts, halogenated materials, and other analytes may be accomplished by IC.
